Scientific References & Clinical Studies

Joint Genesis™ is formulated based on breakthrough research and peer-reviewed studies published by world-leading institutions. Below is a comprehensive list of the scientific literature supporting our formula.

Scientific Research Institutions and Journals Supporting Joint Genesis
  1. Centers for Disease Control and Prevention. Morbidity and Mortality Weekly Report. March 10, 2017. Vol. 66. No. 9.
  2. Sawitzke AD, et al. The effect of glucosamine and/or chondroitin sulfate on the progression of knee OA. Arth Rheum. 2008 Oct;58(10):3183-91.
  3. Wallace IJ, et al. Knee OA has doubled in prevalence since the mid-20th century. Anthropology. August 14, 2017.
  4. Tamer TM. Hyaluronan and synovial joint: function, distribution and healing. Interdiscip Toxicol. 2013;6(3):111-125.
  5. Necas, J., et al. Hyaluronic acid (hyaluronan): A review. Veterinarni Medicina, 53(8), 397–411.
  6. Ingram KR, et al. Cyclic movement stimulates hyaluronan secretion into the synovial cavity of rabbit joints. J Physiol. 2008.
  7. Levick JR. Hyaluronan, the guardian of joints. Physiology News Magazine. [2007]. Issue 67.
  8. Oe, M., et al. Oral hyaluronan relieves knee pain: a review. Nutrition Journal 15, 11 (2015).
  9. Jung H. Hyaluronidase: An overview of its properties, applications, and side effects. Arch Plast Surg. 2020.
  10. Temple-Wong MM, et al. Hyaluronan concentration and size distribution in human knee synovial fluid. Arth Res Ther. 2016.
  11. Nicholls MA, et al. The Disease-Modifying Effects of Hyaluronan in the OA Disease State. Clin Med Insights Arth Musculoskelet Disord. 2017.
  12. Tashiro T, et al. Oral administration of polymer hyaluronic acid alleviates symptoms of knee OA. Scientific World Journal. 2012.
  13. Möller I, et al. Oral administration of a natural extract rich in hyaluronic acid for the treatment of knee OA with synovitis. Clinical Nutrition Supplements 2009.
  14. Kalman DS, et al. Effect of a natural extract of chicken combs with a high content of hyaluronic acid on pain relief. Nutrition Journal 2008.
  15. Martinez-Puig D, et al. Efficacy of oral administration of yoghurt supplemented with Mobilee™ in adults. Mediterranean Journal of Nutrition and Metabolism 2013.
  16. Sánchez J, et al. Blood cell transcriptomics as a source of biomarkers of articular health. Annals of Nutrition and Metabolism 2013.
  17. Moriña D, et al. Efficacy of a Low-fat Yogurt Supplemented with a Rooster Comb Extract on Joint Function. Annals of Nutrition and Metabolism 2013.
  18. Rohdewald PJ. Review on Sustained Relief of OA Symptoms with a Proprietary Extract from Pine Bark. J Med Food. 2018.
  19. Cisár P, et al. Effect of pine bark extract on symptoms of knee OA. Phytother Res. 2008.
  20. Mulek et al. Distribution of Constituents and Metabolites of Maritime Pine Bark Extract into Serum, Blood Cells, and Synovial Fluid. Nutrients. 2017.
  21. Altman RD, et al. Effects of a ginger extract on knee pain in patients with OA. Arthr Rheum. 2001.
  22. Mashhadi NS, et al. Anti-oxidative and anti-inflammatory effects of ginger. Int J Prev Med. 2013.
  23. Bartels EM, et al. Efficacy and safety of ginger in OA patients: a meta-analysis. OA Cartilage. 2015.
  24. Yu G, et al. Effectiveness of Boswellia and Boswellia extract for OA patients: a systematic review. BMC Complement Med Ther. 2020.
  25. Siddiqui MZ. Boswellia serrata, a potential anti-inflammatory agent: an overview. Indian J Pharm Sci. 2011.